Description

3-(2-Benzimidazolyl)Alanine is a non-proteinogenic amino acid derivative featuring a benzimidazole moiety, a structure of significant interest in medicinal chemistry and biochemical research. This compound serves as a versatile building block for the synthesis of novel peptides and pharmaceutical intermediates, enabling the exploration of structure-activity relationships. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, particularly for developing enzyme inhibitors and probing biological pathways.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, especially protease inhibitors and kinase inhibitors.
• Biochemical Research: Used as a specialized amino acid analog in peptide synthesis to study protein structure, function, and interactions.
• Enzyme Inhibition Studies: The benzimidazole core can act as a pharmacophore for designing and testing new enzyme inhibitors.
• Ligand Synthesis: Employed in the creation of chelating agents or ligands for metal complexes in catalytic or diagnostic applications.
• Agrochemical Research: Potential building block for developing new active ingredients with specific biological activity.
• Material Science: Can be incorporated into polymers or specialty chemicals to impart unique properties.

Basic Information

Product Name	3-(2-Benzimidazolyl)Alanine
CAS No.	81440-45-1
Molecular Formula	C10H9N3O2
Molecular Weight	203.20 g/mol
Synonyms	2-(1H-Benzimidazol-2-yl)-3-aminopropanoic Acid; β-(2-Benzimidazolyl)-DL-alanine; 3-(1H-Benzimidazol-2-yl)alanine; 3-(2-Benzimidazolyl)-DL-alanine; DL-3-(2-Benzimidazolyl)alanine; (RS)-3-(1H-Benzimidazol-2-yl)alanine; 2-Benzimidazolepropanoic acid, α-amino-; 81440-45-1
EINECS	Contact for details

Quality Control

Our 3-(2-Benzimidazolyl)Alanine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity research-grade standards. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.