Description

R(-)-Propylnorapomorphine Hcl is a high-purity, chiral aporphine alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical reference standard and a key intermediate for synthesizing novel dopaminergic agents. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in neuroscience and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in the production of active pharmaceutical ingredients (APIs).
• Neuroscience Research: Acts as a potent and selective dopamine receptor ligand for in vitro and in vivo pharmacological studies.
• Drug Discovery Intermediate: Serves as a key chiral building block in the synthetic pathways for novel therapeutics targeting Parkinson's disease and other neurological disorders.
• Biochemical Assay Development: Employed in high-throughput screening (HTS) campaigns to identify and characterize new drug candidates.
• Academic Research: Utilized in university and institutional labs for fundamental studies on dopamine receptor structure, function, and signaling pathways.

Basic Information

Product Name	R(-)-Propylnorapomorphine Hcl
CAS No.	18426-20-5
Molecular Formula	C19H24ClNO2
Molecular Weight	333.86 g/mol
Synonyms	(-)-10,11-Dimethoxyaporphine-6-propylamine hydrochloride; (R)-(-)-N-Propylnorapomorphine hydrochloride; R-(-)-N-Propylnorapomorphine HCl; R(-)-NPA HCl; (6aR)-5,6,6a,7-Tetrahydro-6-propyl-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride; Propylnorapomorphine hydrochloride; 6-Propylnorapomorphine HCl
EINECS	Contact for details

Quality Control

Our R(-)-Propylnorapomorphine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) providing full characterization data, including identity, purity, and impurity profile, is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (R-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.