Description

4-Benzyloxy-3-Fluoro-Phenol is a high-purity fluorinated phenolic compound, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a benzyl-protected phenol and a fluorine substituent, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic components for electronic display and lighting materials.
• Polymer Science: Acts as a monomer or modifier in the creation of specialty polymers with enhanced thermal and chemical resistance.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new fluorination reactions and protecting group strategies.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	4-Benzyloxy-3-Fluoro-Phenol
CAS No.	81228-25-3
Molecular Formula	C₁₃H₁₁FO₂
Molecular Weight	218.22 g/mol
Synonyms	3-Fluoro-4-(phenylmethoxy)phenol; 4-(Benzyloxy)-3-fluorophenol; Phenol, 4-(benzyloxy)-3-fluoro-; 3-Fluoro-4-benzyloxyphenol; 4-Benzyloxy-3-fluorophenol; 81228-25-3; 4-(Phenylmethoxy)-3-fluorophenol
EINECS	Contact for details

Quality Control

Every batch of 4-Benzyloxy-3-Fluoro-Phenol is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure it meets the high standards required for research and industrial synthesis. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, which include data for purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.