Description

5-Oxo-L-Pro-2-Fluoro-L-His-L-Pro-Nh2 is a specialized fluorinated peptide derivative of significant interest in advanced pharmaceutical research and development. This compound matters for its role as a key intermediate or building block in the synthesis of novel bioactive peptides and peptidomimetics. It is primarily needed by research institutions and pharmaceutical companies focused on developing new therapeutic agents, particularly in areas such as enzyme inhibition and targeted drug delivery.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel peptide-based drugs and therapeutic candidates.
• Protease Inhibitor Research: Used in the development and study of fluorinated peptide analogs designed to inhibit specific enzyme targets.
• Peptidomimetic Design: Acts as a core structure for creating stable, bioavailable mimetics of natural peptide hormones.
• Bioconjugation & Labeling: Utilized in the preparation of labeled peptides for diagnostic imaging or biochemical tracing studies.
• Chemical Biology Probes: Employed to create specialized probes for investigating enzyme mechanisms and protein-protein interactions.
• Academic & Industrial R&D: Essential raw material for exploratory chemistry in both university laboratories and corporate R&D divisions.

Basic Information

Product Name	5-Oxo-L-Pro-2-Fluoro-L-His-L-Pro-Nh2
CAS No.	81222-56-2
Molecular Formula	C16H22FN7O4
Molecular Weight	395.39 g/mol
Synonyms	2-Fluoro-L-histidyl-5-oxo-L-prolyl-L-prolinamide; 5-Oxo-L-prolyl-2-fluoro-L-histidyl-L-prolinamide; Fmoc-2-F-His(Trt)-OH derivative precursor; Fluorinated Tripeptide Amide; (2S)-2-[[(2S)-5-Oxo-1-pyrrolidinyl]carbonyl]amino]-3-(2-fluoro-1H-imidazol-4-yl)propanoyl]-L-prolinamide; L-Pro-NH2, 5-oxo-L-Pro-2-fluoro-L-His-; Peptide building block 81222-56-2
EINECS	Contact for details

Quality Control

Our 5-Oxo-L-Pro-2-Fluoro-L-His-L-Pro-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via mass spectrometry and NMR, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.