Description

n-Formylmethionyl-Leucyl-Phenylalanyl-Lysine is a synthetic formyl tripeptide derivative of significant interest in biochemical and pharmacological research. This compound serves as a key tool for studying the mechanisms of chemotaxis and inflammation, particularly in relation to formyl peptide receptor (FPR) signaling pathways. It is primarily utilized by researchers and developers in the life sciences sector for investigating immune cell activation and developing novel therapeutic agents.

Application

• Biochemical Research: A critical tool for studying formyl peptide receptor (FPR) activation, signal transduction, and downstream cellular responses in neutrophils and other immune cells.
• Inflammation & Immunology Studies: Used to model and investigate the molecular mechanisms of chemotaxis, phagocytosis, and the release of inflammatory mediators.
• Drug Discovery & Screening: Serves as a reference standard and agonist in high-throughput screening assays to identify and characterize new FPR modulators or anti-inflammatory compounds.
• Cell Signaling Pathways: Employed in academic and industrial laboratories to elucidate the role of formylated peptides in host defense and disease pathology.
• Pharmacology Assays: Utilized in vitro and ex vivo to assess receptor binding affinity, potency, and efficacy of candidate drug molecules targeting the FPR family.

Basic Information

Product Name	n-Formylmethionyl-Leucyl-Phenylalanyl-Lysine
CAS No.	81213-55-0
Molecular Formula	C31H49N5O7S
Molecular Weight	635.82 g/mol
Synonyms	fMLFK; N-Formyl-Met-Leu-Phe-Lys; Formyl-Methionyl-Leucyl-Phenylalanyl-Lysine; fMet-Leu-Phe-Lys; Formyl Peptide fMLFK; Chemotactic Peptide fMLFK; For-MLF-K; Formylmethionylleucylphenylalanyllysine
EINECS	Contact for details

Quality Control

Our n-Formylmethionyl-Leucyl-Phenylalanyl-Lysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.