Description

D-Isoleucine, 3-Methoxy- (9Ci) is a chemically modified derivative of the essential amino acid isoleucine, featuring a methoxy group at the 3-position. This structural modification imparts unique steric and electronic properties, making it a valuable non-natural amino acid building block for advanced research and synthesis. It is primarily utilized by researchers and process chemists in the pharmaceutical and biotechnology sectors. The compound is supplied with full traceability under CAS NO 81202-43-9.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate modified amino acid residues, enabling the study of structure-activity relationships (SAR).
• Biochemical Research: Acts as a substrate analog in enzymatic studies to investigate amino acid metabolism, transport mechanisms, and enzyme inhibition.
• Proteomics & Labeling: Potential utility in the design of isotopic labels or fluorescent tags for mass spectrometry and protein tracking studies.
• Ligand Development: Employed in the synthesis of specialized ligands for asymmetric catalysis or as a component in metal-organic frameworks (MOFs).

Basic Information

Product Name	D-Isoleucine, 3-Methoxy- (9Ci)
CAS No.	81202-43-9
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Synonyms	D-3-Methoxyisoleucine; (2R,3R)-2-Amino-3-methoxy-4-methylpentanoic acid; (R,R)-3-Methoxyisoleucine; 3-Methoxy-D-isoleucine; 4-Methyl-3-methoxy-D-norvaline; D-3-MeO-Ile; (2R,3R)-3-Methoxy-4-methylnorvaline
EINECS	Contact for details

Quality Control

Our D-Isoleucine, 3-Methoxy- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing batch-specific results for identity, purity, and related substances is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.