Description

L-Aspartic-4-13C Acid is a stable isotope-labeled derivative of the essential amino acid L-aspartic acid, specifically enriched with carbon-13 at the 4-position. This precise labeling makes it an indispensable tool for advanced metabolic research, drug development, and analytical chemistry, providing critical insights into biochemical pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers of diagnostic reagents and isotopic standards.

Application

• Metabolic Pathway Tracing: Used as a 13C-labeled tracer in NMR and mass spectrometry studies to investigate amino acid metabolism, the citric acid cycle, and urea cycle dynamics.
• Pharmaceutical Research & Development: Serves as a key building block in the synthesis of isotopically labeled peptides, proteins, and potential drug candidates for pharmacokinetic and pharmacodynamic (PK/PD) studies.
• Internal Standard for Quantitative Analysis: Employed in LC-MS and GC-MS as a high-purity internal standard for the accurate quantification of L-aspartic acid and related compounds in complex biological matrices.
• Nutritional Science Research: Facilitates studies on protein synthesis, turnover, and amino acid requirements in humans and animals using stable isotope techniques.
• Diagnostic Reagent Manufacturing: A critical raw material in producing calibrated standards and reagents for clinical mass spectrometry assays.

Basic Information

Product Name	L-Aspartic-4-13C Acid
CAS No.	81201-98-1
Molecular Formula	C313CH7NO4
Molecular Weight	134.09 g/mol (for 13C4 labeled form)
Synonyms	(2S)-2-Aminobutanedioic-4-13C Acid; L-Aspartic Acid-4-13C; Aspartic-4-13C Acid; (S)-Aminosuccinic-4-13C Acid; H-Asp(4-13C)-OH; L-Aspartic Acid (4-13C); 13C Labeled L-Aspartic Acid; L-2-Aminobutanedioic-4-13C Acid
EINECS	Contact for details

Quality Control

Every batch of our L-Aspartic-4-13C Acid is manufactured and tested under strict quality systems to ensure exceptional isotopic and chemical purity, critical for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) detailing isotopic enrichment (typically ≥99 atom % 13C), chemical purity (by HPLC), chiral purity, and specific tests for identity and impurities. Our quality commitment aligns with the standards expected for research-grade biochemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccated conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Isotopic Enrichment	≥99 atom % 13C
Assay (HPLC)	≥98.0%
Optical Rotation	[α]20/D: +24.5° to +26.0° (c=1 in 5N HCl)
Chiral Purity (HPLC)	≥99.0% L-isomer
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.