Description

L-Aspartic Acid (1-13C) is a stable isotope-labeled analog of the essential amino acid L-aspartic acid, where the carbon at the 1-position is enriched with the carbon-13 isotope. This compound is critical for advanced research and development, enabling precise metabolic pathway tracing and quantitative analysis in complex biological systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications in nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and metabolic studies.

Application

• Metabolic Flux Analysis (MFA): As a 13C-labeled tracer for studying central carbon metabolism, glycolysis, and the TCA cycle in cell cultures and microorganisms.
• Biomolecular NMR Spectroscopy: Used for protein structure determination, dynamics studies, and drug discovery by providing site-specific isotopic labeling to simplify complex spectra.
• Mass Spectrometry (MS) Standards: Serves as an internal standard for the accurate quantification of aspartic acid and related metabolites in LC-MS and GC-MS platforms.
• Pharmaceutical Research: Employed in the development and testing of new drugs, particularly in pharmacokinetics and metabolism studies to track drug disposition.
• Nutritional Science Research: Used in studies investigating amino acid metabolism, protein synthesis, and nutritional bioavailability.
• Industrial Biotechnology: Applied in metabolic engineering of microbial strains for the optimized production of biochemicals and amino acids.

Basic Information

Product Name	L-Aspartic Acid (1-13C)
CAS No.	81201-97-0
Molecular Formula	C413CH7NO4
Molecular Weight	134.10 g/mol (for 13C1 isotopologue)
Synonyms	(2S)-2-Aminobutanedioic-1-13C Acid; L-Aspartic-1-13C Acid; (S)-(+)-Aspartic-1-13C Acid; Aspartic Acid (L-13C1); (S)-Aminosuccinic-1-13C Acid; H-Asp(13COOH)-OH; 1-13C-L-Aspartic Acid; 13C-Labeled L-Aspartic Acid
EINECS	Contact for details

Quality Control

Our L-Aspartic Acid (1-13C) is manufactured under strict quality systems to ensure high isotopic and chemical purity for research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (Atom % 13C), chemical purity (by HPLC), chiral purity, and specific tests for identity. We support compliance with relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to 13C labeling pattern
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 99 atom % 13C
Optical Rotation	[α]D20: +24.5° to +26.0° (c=1 in 5N HCl)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.