Description

H-Thr-Tyr-Ser-Oh CAS NO 81161-89-9 is a synthetic tripeptide composed of L-Threonine, L-Tyrosine, and L-Serine, terminated with a free carboxylic acid group. This compound serves as a crucial building block and intermediate in advanced pharmaceutical research and peptide synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of longer, complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate, standard, or model compound in enzymatic studies, receptor-ligand binding assays, and metabolic pathway investigations.
• Peptide Library Construction: An essential component in combinatorial chemistry for creating diverse peptide libraries used in drug discovery and screening.
• Cosmeceutical Development: Investigated for potential use in bioactive skincare formulations targeting specific skin receptors or enzymes.
• Diagnostic Reagent Synthesis: Serves as a precursor for labeled peptides used in diagnostic kits and imaging agents.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental research in peptide chemistry and molecular biology.

Basic Information

Product Name	H-Thr-Tyr-Ser-Oh
CAS No.	81161-89-9
Molecular Formula	C₁₆H₂₃N₃O₇
Molecular Weight	369.37 g/mol
Synonyms	H-Thr-Tyr-Ser-OH; L-Threonyl-L-tyrosyl-L-serine; Thr-Tyr-Ser; TYS; H-L-Thr-L-Tyr-L-Ser-OH; Tripeptide TYS; (2S,3R)-2-[[(2S)-2-[[(2S)-2-Amino-3-hydroxybutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxypropanoic acid; L-Thr-L-Tyr-L-Ser
EINECS	Contact for details

Quality Control

Our H-Thr-Tyr-Ser-Oh is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring compliance with research and development standards. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Total)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.