Description

Proline, 1-Methylethyl Ester (9Ci) is a specialized proline derivative, an ester of the amino acid proline. This compound is valued as a versatile chiral building block and intermediate in advanced organic synthesis, particularly for introducing the proline moiety into complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the synthesis of peptide mimetics, protease inhibitors, and other bioactive molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators that incorporate proline-based structures.
• Asymmetric Catalysis: Acts as a precursor for ligands or organocatalysts used in stereoselective chemical transformations.
• Peptide Chemistry: Employed in the preparation of modified peptides and peptidomimetics for biochemical and therapeutic research.
• Fine Chemical Synthesis: A building block for creating specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: Essential for methodological development and exploratory synthesis in organic chemistry laboratories.

Basic Information

Product Name	Proline, 1-Methylethyl Ester (9Ci)
CAS No.	81084-79-9
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	L-Proline isopropyl ester; Isopropyl L-prolinate; 1-Methylethyl prolinate; Proline isopropyl ester; (S)-Proline 1-methylethyl ester; Proline, isopropyl ester; (S)-1-(Isopropoxycarbonyl)pyrrolidine-2-carboxylic acid (precursor form); 2-Pyrrolidinecarboxylic acid, 1-methylethyl ester, (S)-
EINECS	Contact for details

Quality Control

Our Proline, 1-Methylethyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.