Description

3-(3-Chloro-2-Methylphenyl)-2-Thioxo-2,3-Dihydro-4(1H)-Quinazolinone is a specialized heterocyclic organic compound belonging to the quinazolinone class, which is a key scaffold in medicinal chemistry. This compound matters as a versatile and high-purity building block for pharmaceutical research and development, enabling the synthesis of novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new molecular entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates targeting various biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Agrochemical Development: Acts as a key intermediate in the research and production of novel pesticides and herbicides.
• Chemical Biology Probe Synthesis: Utilized in the creation of molecular probes for studying enzyme function and cellular processes.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for exploratory synthetic chemistry and new methodology development.

Basic Information

Product Name	3-(3-Chloro-2-Methylphenyl)-2-Thioxo-2,3-Dihydro-4(1H)-Quinazolinone
CAS No.	81066-84-4
Molecular Formula	C15H11ClN2OS
Molecular Weight	302.78 g/mol
Synonyms	3-(3-Chloro-2-methylphenyl)-2-sulfanylidene-1,3-dihydroquinazolin-4-one; 3-(3-Chloro-2-methylphenyl)-2-thioxo-1,2,3,4-tetrahydro-4-quinazolinone; 4(1H)-Quinazolinone, 2,3-dihydro-3-(3-chloro-2-methylphenyl)-2-thioxo-; 81066-84-4; Quinazolinone derivative, 3-(3-chloro-2-methylphenyl)-2-thioxo-; 2-Thioxo-3-(3-chloro-2-methylphenyl)-2,3-dihydro-4(1H)-quinazolinone
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-2-Methylphenyl)-2-Thioxo-2,3-Dihydro-4(1H)-Quinazolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every lot and provided upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.