Description

n-α-Acetyl-L-Lysine-n-Methylamide Monohydrate is a high-purity, protected derivative of the essential amino acid L-Lysine, designed for advanced research and synthesis. This compound is critical for peptide chemistry, serving as a key building block to introduce modified lysine residues with specific functional properties. It is primarily utilized by pharmaceutical researchers, biochemists, and fine chemical manufacturers developing novel therapeutic peptides, biochemical probes, and specialty active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis: A crucial protected intermediate for the solid-phase and solution-phase synthesis of complex peptides and proteins.
• Pharmaceutical Research: Used in the development and production of peptide-based drug candidates, including hormone analogs and enzyme inhibitors.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides or cross-linkers used in biochemical assays and diagnostic tools.
• Biochemical Studies: Employed in academic and industrial research to study protein-protein interactions, enzyme mechanisms, and post-translational modifications.
• Fine Chemical Intermediate: Acts as a specialized building block for synthesizing more complex chiral molecules in custom synthesis projects.

Basic Information

Product Name	n-α-Acetyl-L-Lysine-n-Methylamide Monohydrate
CAS No.	81013-00-5
Molecular Formula	C9H19N3O3 • H2O
Molecular Weight	235.28 g/mol (Anhydrous basis: 217.27)
Synonyms	Nα-Acetyl-L-lysine N-methylamide monohydrate; Ac-Lys-NHMe • H2O; (S)-2-Acetamido-6-(methylamino)hexanamide monohydrate; N-Acetyl-L-lysine methylamide monohydrate; L-Lysine, N2-acetyl-, N6-methylamide, monohydrate; Protected L-Lysine derivative; Ac-Lys-NH-CH3 • H2O
EINECS	Contact for details

Quality Control

Our n-α-Acetyl-L-Lysine-n-Methylamide Monohydrate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and cGMP applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards, and custom purity grades or specific analytical protocols can be accommodated upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccated or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+15.0° to +20.0° (c=1 in H2O)
Water Content (KF)	6.0% - 8.5%
Heavy Metals (as Pb)	≤10 ppm
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.