Description

Cholecystokinin (1-14) CAS NO 80980-82-1 is a bioactive peptide fragment of the gastrointestinal hormone cholecystokinin, specifically comprising its first 14 amino acids. This compound is a critical research tool for studying digestive physiology, pancreatic secretion, and satiety signaling pathways in both academic and pharmaceutical research settings. It is primarily utilized by biochemists, pharmacologists, and neuroscientists for receptor binding studies, enzyme activity assays, and the development of diagnostic or therapeutic agents targeting the CCK receptor system.

Application

• Biomedical Research: Fundamental studies on the role of cholecystokinin in digestion, appetite regulation, and pain perception.
• Pharmacological Assays: Used as a reference standard or agonist in in vitro and in vivo assays to characterize CCK receptor subtypes (CCKA and CCKB).
• Drug Discovery: A key starting material or biochemical tool in the screening and development of novel therapeutics for gastrointestinal disorders, obesity, and anxiety.
• Diagnostic Development: Potential use in the formulation of kits for research purposes to measure CCK levels or receptor density.
• Neuroscience Studies: Investigation of CCK's function as a neurotransmitter or neuromodulator in the central and peripheral nervous systems.

Basic Information

Product Name	Cholecystokinin (1-14)
CAS No.	80980-82-1
Molecular Formula	C78H111N19O20S2
Molecular Weight	1690.0 g/mol
Synonyms	CCK (1-14); CCK-8 Precursor; Cholecystokinin Tetradecapeptide; Sincalide fragment (1-14); CCK-14; H-Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 (sequence for CCK-8, core of fragment); Pancreozymin fragment; CCK-PZ (1-14)
EINECS	Contact for details

Quality Control

Our Cholecystokinin (1-14) is produced and controlled under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure it meets the high standards required for critical research applications. A Certificate of Analysis (COA) detailing purity, peptide content, and other relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Solubility	Soluble in water, dilute aqueous acid, or DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.