Description

Benzylpenicilloyl-Heptapeptide is a defined synthetic peptide hapten, structurally related to the penicillin allergen. This compound is of critical importance for research and diagnostic applications in the field of drug hypersensitivity and immunology. It serves as a key reference standard and antigenic probe for investigating IgE-mediated allergic reactions to β-lactam antibiotics. Professionals in pharmaceutical R&D, immunology research, and in vitro diagnostic (IVD) kit manufacturing require this high-purity material for method development, assay calibration, and specificity testing.

Application

• Immunological Research: Used as a defined hapten to study the mechanism of penicillin allergy and cross-reactivity patterns.
• Diagnostic Assay Development: Serves as a critical antigen component in the development and validation of in vitro tests (e.g., ELISA, ImmunoCAP) for detecting penicillin-specific IgE antibodies.
• Reference Standard: Employed as a certified reference material (CRM) for quality control and standardization of commercial allergy diagnostic kits.
• Antigen Specificity Studies: Utilized to map B-cell and T-cell epitopes involved in β-lactam hypersensitivity reactions.
• Bioconjugation: Acts as a well-characterized hapten for conjugation to carrier proteins (e.g., HSA, BSA) to produce immunogens or solid-phase antigens.
• Method Validation: Essential for establishing the specificity, sensitivity, and reproducibility of new analytical methods in clinical immunology laboratories.

Basic Information

Item	Detail
Product Name	Benzylpenicilloyl-Heptapeptide
CAS No.	80976-69-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BPO-Heptapeptide; Penicilloyl Heptapeptide; Benzylpenicilloyl Poly-L-lysine Heptamer; BPO-PLL (Heptamer); Penicilloyl Hapten Heptapeptide; Allergen Penicilloyl Heptapeptide; IgE Penicilloyl Antigen Heptapeptide; BPO-Hepta
EINECS	Contact for details

Quality Control

Our Benzylpenicilloyl-Heptapeptide is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research and diagnostic applications. Each lot undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation. We provide comprehensive Certificates of Analysis (COA) detailing all specifications. Production can adhere to relevant quality management standards, including ISO 13485 for IVD applications, upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. This material is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.