Description

2-Homopiperidino-Methyl-3-(2-Tolyl)-4-(3H)-6-Iodoquinazolone is a sophisticated heterocyclic organic compound featuring a quinazolone core, strategically functionalized with iodine and a homopiperidine moiety. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel drug candidates, particularly those targeting complex disease pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential therapeutic agents, especially in oncology and CNS drug discovery programs.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and library synthesis due to its modifiable functional groups.
• Chemical Biology Probe Development: Used in the design and creation of molecular probes for studying biological targets and mechanisms of action.
• Process Chemistry & Scale-Up: Employed in the development and optimization of synthetic routes for active pharmaceutical ingredients (APIs) at various scales.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis projects and novel heterocycle chemistry.

Basic Information

Product Name	2-Homopiperidino-Methyl-3-(2-Tolyl)-4-(3H)-6-Iodoquinazolone
CAS No.	80930-91-2
Molecular Formula	C21H22IN3O
Molecular Weight	459.33 g/mol
Synonyms	6-Iodo-2-[(hexahydro-1H-azepin-1-yl)methyl]-3-(2-methylphenyl)-4(3H)-quinazolinone; 2-[(Hexahydro-1H-azepin-1-yl)methyl]-6-iodo-3-(2-methylphenyl)-4(3H)-quinazolinone; 2-(Homopiperidin-1-ylmethyl)-3-o-tolyl-6-iodoquinazolin-4(3H)-one; 80930-91-2; 6-Iodo-2-(homopiperidin-1-ylmethyl)-3-(2-methylphenyl)quinazolin-4(3H)-one
EINECS	Contact for details

Quality Control

Every batch of 2-Homopiperidino-Methyl-3-(2-Tolyl)-4-(3H)-6-Iodoquinazolone is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are supported by a detailed Certificate of Analysis (COA) that includes data from HPLC, NMR, and mass spectrometry. We are committed to meeting the stringent requirements of GMP-grade intermediates and research chemicals, with specifications available to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.