Description

2(1H)-Pyrimidinone, 4-Chloro- (6Ci,9Ci) is a halogenated pyrimidinone derivative, a versatile heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its reactive chloro substituent, which enables precise functionalization for creating complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of nucleoside analogs, antiviral agents, and other bioactive heterocyclic compounds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyrimidine core's biological activity.
• Organic Synthesis Building Block: Serves as a versatile precursor for cross-coupling reactions, nucleophilic substitutions, and other transformations to create complex molecules.
• Material Science Research: Investigated as a monomer or functional component in the synthesis of specialty polymers and advanced organic materials.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.

Basic Information

Item	Details
Product Name	2(1H)-Pyrimidinone, 4-Chloro- (6Ci,9Ci)
CAS No.	80927-55-5
Molecular Formula	C4H3ClN2O
Molecular Weight	130.53 g/mol
Synonyms	4-Chloro-2(1H)-pyrimidinone; 4-Chloro-1H-pyrimidin-2-one; 4-Chloropyrimidin-2(1H)-one; 4-Chloro-2-hydroxypyrimidine; 2-Hydroxy-4-chloropyrimidine; 4-Chloro-2-pyrimidinol; 4-Chloro-1,2-dihydropyrimidin-2-one
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-2(1H)-pyrimidinone is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.