Description

H-D-Phe-Ala-Oh is a high-purity dipeptide building block, specifically the L-alanine derivative of D-phenylalanine. This compound is a critical intermediate in advanced peptide synthesis, offering precise stereochemical control for research and development. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on developing novel therapeutic peptides, peptidomimetics, and biochemical probes.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of complex therapeutic peptides targeting metabolic disorders, oncology, and CNS diseases.
• Biochemical Research: Used in structure-activity relationship (SAR) studies to investigate peptide-receptor interactions and enzyme specificity.
• Peptidomimetic Development: Serves as a core scaffold for designing and synthesizing non-natural peptide analogs with enhanced stability and bioavailability.
• Reference Standard: Employed as a high-purity analytical standard in HPLC and LC-MS methods for quality control and metabolic studies of peptide-based drugs.
• Proteomics & Labeling: Can be incorporated into custom peptide sequences for mass spectrometry-based proteomic analysis or as a component of affinity tags.

Basic Information

Product Name	H-D-Phe-Ala-Oh
CAS No.	80924-58-9
Molecular Formula	C12H16N2O3
Molecular Weight	236.27 g/mol
Synonyms	H-D-Phe-L-Ala-OH; (R)-2-((S)-2-Amino-3-phenylpropanamido)propanoic acid; D-Phenylalanyl-L-alanine; Ala-D-Phe; D-Phe-Ala; D-Phenylalanine-L-alanine dipeptide; N-(D-Phenylalanyl)-L-alanine
EINECS	Contact for details

Quality Control

Our H-D-Phe-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via IR and MS. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.