Description

(S)-2-Amino-6-Phenylhexanoic Acid CAS NO 80887-26-9 is a chiral, non-proteinogenic amino acid derivative featuring a phenylalkyl side chain. This compound serves as a critical chiral building block and intermediate in the synthesis of complex pharmaceutical molecules and bioactive peptides. It is essential for research and development in medicinal chemistry, particularly for organizations developing enzyme inhibitors, peptide-based therapeutics, and novel drug candidates requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially peptidomimetics and enzyme inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a hydrophobic, aromatic moiety into peptide sequences for structure-activity relationship (SAR) studies.
• Medicinal Chemistry Research: Serves as a building block in drug discovery programs for creating libraries of novel compounds targeting various diseases.
• Biochemical Tool: Employed in biochemical assays and as a substrate analog to study enzyme mechanisms and inhibition.
• Asymmetric Synthesis: Utilized as a starting material or auxiliary in asymmetric catalytic reactions to induce chirality in target molecules.

Basic Information

Product Name	(S)-2-Amino-6-Phenylhexanoic Acid
CAS No.	80887-26-9
Molecular Formula	C12H17NO2
Molecular Weight	207.27 g/mol
Synonyms	(S)-2-Amino-6-phenylhexanoic acid; (S)-6-Phenylnorleucine; (S)-2-Amino-6-phenylcaproic acid; (S)-α-Amino-ω-phenylhexanoic acid; (S)-Hph; (S)-2-Amino-6-phenyl-n-hexanoic acid; L-2-Amino-6-phenylhexanoic acid; (2S)-2-Amino-6-phenylhexanoic acid
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-6-Phenylhexanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) confirming identity, purity (typically ≥98%), and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.