Description

5-Ethyl-5-(p-Hydroxy- Phenyl)Barbituric Acid is a specialized barbiturate derivative, a key intermediate in the synthesis of more complex pharmaceutical compounds. Its value lies in its defined chemical structure, which serves as a crucial building block for research and development in medicinal chemistry. This product is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in developing new therapeutic agents or studying barbiturate chemistry.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel barbiturate-based active pharmaceutical ingredients (APIs) and potential therapeutic agents.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and drug discovery programs targeting the central nervous system.
• Reference Standard: Serves as an analytical standard for quality control and method development in laboratories analyzing barbiturate compounds.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to create more complex, functionalized molecules for specialized applications.
• Biochemical Research: Potential use in studying the interaction of barbiturates with biological receptors and enzymes.

Basic Information

Product Name	5-Ethyl-5-(p-Hydroxy- Phenyl)Barbituric Acid
CAS No.	80866-89-3
Molecular Formula	C12H12N2O4
Molecular Weight	248.24 g/mol
Synonyms	5-Ethyl-5-(4-hydroxyphenyl)barbituric acid; 5-Ethyl-5-(4-hydroxyphenyl)-2,4,6(1H,3H,5H)-pyrimidinetrione; 5-(4-Hydroxyphenyl)-5-ethylbarbituric acid; Phenobarbital related compound B (4'-Hydroxy Phenobarbital); 4'-Hydroxyphenobarbital; p-Hydroxyphenobarbital
EINECS	Contact for details

Quality Control

Our 5-Ethyl-5-(p-Hydroxy- Phenyl)Barbituric Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and fine chemical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.