Description

Cholecystokinin Octapeptide (1-4) (Desulfated) is a synthetic bioactive peptide fragment derived from the gastrointestinal hormone cholecystokinin. This compound is a critical research tool for studying receptor binding, signal transduction, and the physiological roles of CCK in the brain and digestive system. It is essential for pharmaceutical R&D, academic research, and diagnostic development focused on neurological disorders, appetite regulation, and pancreatic function.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies of CCK receptor subtypes (CCKA and CCKB) in the central nervous system.
• Pharmacological Assays: Serves as a key ligand in competitive binding assays and functional tests to screen and characterize novel therapeutic compounds.
• Biochemical Studies: Employed to investigate the structure-activity relationship (SAR) of CCK peptides and the role of sulfation in biological activity.
• Diagnostic Development: Acts as a critical component in the development of immunoassays and other diagnostic tools for metabolic and gastrointestinal research.
• Academic & Institutional Research: Fundamental reagent for university and institutional labs exploring gastroenterology, endocrinology, and behavioral science.

Basic Information

Product Name	Cholecystokinin Octapeptide (1-4) (Desulfated)
CAS No.	80790-40-5
Molecular Formula	C38H55N9O9S
Molecular Weight	813.97 g/mol
Synonyms	CCK-8 (1-4), Desulfated; CCK Octapeptide (1-4), Desulfated; Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2 (1-4), Desulfated; Cholecystokinin Fragment 1-4, Desulfated; Sincalide (1-4) Fragment, Desulfated; CCK-4, Desulfated; H-Asp-Tyr-Met-Gly-OH (Desulfated); Tyr-Met-Gly-Trp Peptide Fragment
EINECS	Contact for details

Quality Control

Our Cholecystokinin Octapeptide (1-4) (Desulfated) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide comprehensive Certificates of Analysis (COA) detailing all specifications to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.