Description

Bovine Parathyroid Hormone (41-84) is a specific, biologically active fragment of the full-length parathyroid hormone. This peptide is crucial for research into calcium and phosphate metabolism, bone physiology, and endocrine signaling pathways. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical developers focused on metabolic bone diseases and hormone receptor studies. The compound, identified by CAS No. 80700-73-8, is supplied to meet the stringent requirements of advanced life science applications.

Application

• Biochemical Research: Used as a standard or reagent in studies of parathyroid hormone (PTH) receptor binding, activation, and downstream signaling cascades.
• Drug Discovery & Development: Serves as a critical reference material and pharmacological tool in screening programs for osteoporosis, hyperparathyroidism, and related metabolic disorders.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to investigate the effects of PTH on osteoblast and osteoclast activity, renal tubular function, and calcium homeostasis.
• Antibody & Assay Development: Acts as an antigen for the production and validation of specific antibodies, or as a calibrator in immunoassay development (e.g., ELISA).
• Structure-Activity Relationship (SAR) Studies: Employed to map the functional domains of parathyroid hormone and design novel peptide analogs or mimetics.
• Academic & Educational Use: Provides a high-purity reference compound for teaching and advanced research in endocrinology and molecular biology laboratories.

Basic Information

Item	Detail
Product Name	Bovine Parathyroid Hormone (41-84)
CAS No.	80700-73-8
Molecular Formula	C212H351N65O61S2
Molecular Weight	Approx. 4850.6 g/mol
Synonyms	Parathyroid Hormone (41-84), bovine; PTH (41-84); Bovine PTH Fragment (41-84); Parathyrin (41-84); Parathormone (41-84); PTH 41-84; bPTH(41-84); N-terminal truncated parathyroid hormone
EINECS	Contact for details

Quality Control

Our Bovine Parathyroid Hormone (41-84) is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and MS for identity confirmation. A Certificate of Analysis (COA) detailing purity, peptide content, and analytical data is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under inert atmosphere or vacuum desiccation.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.