Description

Enkephalin-Leu, Arg(6)-Phenh2(7)- is a synthetic peptide analog of the endogenous opioid peptide enkephalin, featuring specific amino acid substitutions at positions 6 and 7. This compound is of significant interest in advanced biochemical and pharmacological research for studying opioid receptor interactions and signal transduction pathways. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on neuroscience, pain management, and peptide-based drug discovery.

Application

• Neuroscience Research: As a tool compound for investigating the structure-activity relationships (SAR) of enkephalin peptides with delta (δ) and mu (μ) opioid receptors.
• Pharmacological Studies: Used in in vitro and ex vivo assays to study opioid receptor binding affinity, selectivity, and downstream cellular effects.
• Drug Discovery & Development: Serves as a reference standard or a lead compound in the design and screening of novel analgesic and neuroprotective agents.
• Biochemical Reagent: Employed in enzymatic stability studies and metabolic pathway analysis related to peptide degradation.
• Academic Research: Fundamental research in universities and institutes exploring the endogenous opioid system and peptide biochemistry.

Basic Information

Product Name	Enkephalin-Leu, Arg(6)-Phenh2(7)-
CAS No.	80690-78-4
Molecular Formula	C36H52N10O8
Molecular Weight	752.87 g/mol
Synonyms	[Arg6, Phe-NH27]-Leu-Enkephalin; H-Tyr-Gly-Gly-Phe-Leu-Arg-Phe-NH2; Leu-Enkephalin, [Arg6,Phe-NH27]-; L-Enkephalin, 6-L-arginine-7-phenylalaninamide-; Opioid peptide analog 80690-78-4; YGGFLRF-NH2; [Arg6, Phe-NH27]-Leu-Enkephalin acetate
EINECS	Contact for details

Quality Control

Our peptide products are manufactured and analyzed under strict quality management systems. Certificates of Analysis (COA) are provided with each batch, detailing purity, identity, and other critical parameters. Standard quality control includes rigorous testing via HPLC for purity assessment and Mass Spectrometry (MS) for identity confirmation, ensuring compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Conforms
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.