Description

Phenylalanyl-Leucyl-Arginyl Phenylalaninamide CAS NO 80690-77-3 is a synthetic tetrapeptide sequence of significant interest in biochemical research and pharmaceutical development. This compound is valued for its role as a model substrate and a key structural motif in studying enzyme kinetics, peptide stability, and receptor-ligand interactions. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in proteomics, drug discovery, and the synthesis of bioactive peptide analogs.

Application

• Biochemical Research: Serves as a critical substrate or inhibitor in enzymatic assays, particularly for studies involving proteases, peptidases, and signal transduction pathways.
• Pharmaceutical R&D: Used as a building block or reference standard in the discovery and development of novel peptide-based therapeutics targeting various diseases.
• Proteomics & Molecular Biology: Employed in studies of protein-protein interactions, peptide mapping, and the investigation of specific amino acid sequence effects on biological activity.
• Academic Research: A valuable tool in university and institutional labs for teaching advanced peptide chemistry and conducting fundamental life science research.
• Fine Chemical Synthesis: Acts as an intermediate for the custom synthesis of longer, more complex peptides with specific biological functions.
• Diagnostic Development: Potential use in the development of diagnostic kits and assays that rely on specific peptide sequences for detection.

Basic Information

Product Name	Phenylalanyl-Leucyl-Arginyl Phenylalaninamide
CAS No.	80690-77-3
Molecular Formula	C34H51N9O5
Molecular Weight	665.83 g/mol
Synonyms	Phe-Leu-Arg-Phe-NH2; H-Phe-Leu-Arg-Phe-NH2; FLRF-NH2; Tetrapeptide FLRF amide; F-L-R-F-NH2; Phenylalanine-Leucine-Arginine-Phenylalaninamide; N-(N-(N-(N-L-Phenylalanyl-L-leucyl)-L-arginyl)-L-phenylalaninamide); L-Phenylalanyl-L-leucyl-L-arginyl-L-phenylalaninamide
EINECS	Contact for details

Quality Control

Our Phenylalanyl-Leucyl-Arginyl Phenylalaninamide is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research-grade specifications. Custom purity grades and analytical packages are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation. For extended storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC-MS)	Conforms
Purity (HPLC)	≥ 95%
Assay (Peptide Content)	≥ 80%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Ratio	Conforms to theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.