Description

3'-β-C-Methyluridine is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical research and development. This compound is valued for its role in the synthesis of novel antiviral and anticancer therapeutics, particularly in the development of modified RNA and nucleotide prodrugs. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors seeking to innovate in nucleoside-based drug discovery.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of antiviral nucleotide analogs, including potential treatments for hepatitis C and other viral infections.
• Anticancer Drug Research: Used in the development of novel chemotherapeutic agents that target RNA synthesis and function in cancer cells.
• Modified RNA Synthesis: Serves as a building block for incorporating stable modifications into oligonucleotides for research and therapeutic applications.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies to understand nucleoside metabolism and related pathways.
• Prodrug Development: Utilized in the design and synthesis of prodrugs to enhance the bioavailability and targeting of nucleoside-based active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Product Name	3'-β-C-Methyluridine
CAS No.	80541-15-7
Molecular Formula	C10H14N2O6
Molecular Weight	258.23 g/mol
Synonyms	3'-C-Methyluridine; 3'-Deoxy-3'-C-methyluridine; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 3'-Methyluridine; Uridine, 3'-C-methyl-; β-C-3'-Methyluridine
EINECS	Contact for details

Quality Control

Our 3'-β-C-Methyluridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture to ensure it meets high-grade standards suitable for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.