Description

Picotamide Monohydrate CAS NO 80530-63-8 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) with significant therapeutic potential. This compound is valued for its antiplatelet and antithrombotic properties, making it a critical component in advanced pharmaceutical research and development. It is primarily sought by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel cardiovascular treatments and other therapeutic agents.

Application

• Pharmaceutical API Synthesis: Serves as a key intermediate or the active ingredient in the production of antiplatelet and antithrombotic medications.
• Cardiovascular Drug Research: Used in preclinical and clinical research for developing new treatments for thrombosis, atherosclerosis, and related circulatory disorders.
• Biochemical Research: Employed as a reference standard or tool compound in pharmacological studies to investigate platelet aggregation pathways.
• Fine Chemical Manufacturing: Utilized in the synthesis of more complex, target-specific molecules for therapeutic applications.
• Contract Manufacturing (CMO/CDMO): Supplied to contract development and manufacturing organizations for GMP-grade production of finished dosage forms.
• Analytical Standard: Acts as a high-purity certified reference material (CRM) for quality control and analytical method development in laboratories.

Basic Information

Product Name	Picotamide Monohydrate
CAS No.	80530-63-8
Molecular Formula	C21H24N4O4 • H2O
Molecular Weight	414.45 g/mol (Monohydrate)
Synonyms	4-Methoxy-N,N'-bis(3-pyridinylmethyl)-1,3-benzenedicarboxamide Monohydrate; G-137; Picotamide; Pirmol; Plactidil; 1,3-Bis(3-pyridylmethyl)-4-methoxyisophthalamide Monohydrate; 4-Methoxy-N,N'-bis(3-pyridylmethyl)isophthalamide Monohydrate
EINECS	Contact for details

Quality Control

Our Picotamide Monohydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, NMR), to ensure it meets stringent specifications for pharmaceutical use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development with research-grade material and can supply GMP-grade product under appropriate quality agreements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0% (on anhydrous basis)
Water Content (KF)	3.5% - 5.0% (Theoretical for monohydrate: ~4.35%)
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.