Description

H-Lys-Trp-Gly-Lys-Oh is a synthetic tetrapeptide sequence featuring lysine and tryptophan residues. This compound is valued for its role as a key intermediate in peptide synthesis and biochemical research, offering precise structural control. It is primarily utilized by research institutions and pharmaceutical developers working on bioactive peptides, enzyme substrates, and novel therapeutic candidates.

Application

• Pharmaceutical Research & Development: Serves as a critical building block (intermediate) for the synthesis of longer, more complex therapeutic peptides.
• Biochemical Studies: Used as a model substrate or inhibitor in enzymatic assays to study protease activity and specificity.
• Peptide Library Construction: Employed in combinatorial chemistry for creating diverse peptide libraries to screen for biological activity.
• Structure-Activity Relationship (SAR) Studies: Acts as a core sequence to investigate how modifications affect peptide binding and function.
• Antimicrobial Peptide (AMP) Research: Investigated as a component in the design of novel peptides with potential antimicrobial properties.
• Cell Penetrating Peptide (CPP) Conjugates: The lysine residues provide positive charges, making it a candidate for conjugation in developing drug delivery vectors.

Basic Information

Product Name	H-Lys-Trp-Gly-Lys-Oh
CAS No.	80496-37-3
Molecular Formula	C27H41N9O5
Molecular Weight	571.68 g/mol
Synonyms	Lys-Trp-Gly-Lys; H-Lys-Trp-Gly-Lys-OH; Lys-Tryptophan-Glycine-Lysine; Tetrapeptide Lys-Trp-Gly-Lys; L-Lysyl-L-tryptophylglycyl-L-lysine; KWGK; KWGK-OH; Peptide Sequence 50-53 (Bovine Pituitary Adenylate Cyclase Activating Polypeptide)
EINECS	Contact for details

Quality Control

Our H-Lys-Trp-Gly-Lys-Oh is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and chiral analysis to ensure stereochemical integrity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (by HPLC)	≥ 97.0% (on anhydrous basis)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.