Description

Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-Nh2 CAS NO 80448-90-4 is a synthetic peptide sequence, also known as a fragment of the dynorphin A family, with significant research and development applications. This compound is valued for its high purity and specificity, making it a critical reagent in advanced biochemical studies. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on neuroscience, peptide chemistry, and drug discovery.

Application

• Neuroscience Research: As a dynorphin-related peptide, it is used in receptor binding studies, signal transduction pathway analysis, and investigations into pain modulation and addiction mechanisms.
• Biochemical Standard: Serves as a high-purity reference standard for analytical method development, validation, and quality control in peptide synthesis.
• Drug Discovery & Development: Acts as a key intermediate or lead compound in the development of novel therapeutics targeting opioid and neuropeptide receptors.
• Academic & Clinical Research: Employed in university and hospital laboratories for fundamental studies on peptide structure-activity relationships (SAR) and physiological functions.
• Biotechnology Reagent: Used in assay development, high-throughput screening (HTS) platforms, and as a tool compound for target validation.

Basic Information

Product Name	Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-Nh2
CAS No.	80448-90-4
Molecular Formula	C99H155N33O23
Molecular Weight	2148.5 g/mol
Synonyms	Dynorphin A (1-17) amide; Dynorphin A (1-17)-NH2; [Des-Tyr]-Dynorphin A (2-17) amide; Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-amide; Dynorphin A amide (1-17); Peptide sequence YGGFLRRIRPKLKWDNQ-NH2
EINECS	Contact for details

Quality Control

Our Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-Nh2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing all specifications is provided to ensure traceability and compliance with your research or development protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation. Allow the vial to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80%
Amino Acid Analysis	± 10% of theoretical
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.