Description

Glycyl-Glycyl-Argininal is a synthetic tripeptide aldehyde derivative of arginine, widely recognized as a potent and selective inhibitor of trypsin-like serine proteases. This compound is crucial for biochemical research and pharmaceutical development due to its ability to modulate key enzymatic pathways. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and biotechnology sectors for applications in enzymology, drug discovery, and proteomics.

Application

• Biochemical Research: As a high-affinity inhibitor for studying the mechanism and kinetics of serine proteases like trypsin, thrombin, and plasmin.
• Pharmaceutical Development: Serves as a key reference standard and pharmacophore in the design of novel therapeutic agents targeting coagulation, inflammation, and oncology pathways.
• Proteomics & Diagnostics: Used in assay development and diagnostic kit formulation to specifically inhibit target proteases in complex biological samples.
• Enzyme Characterization: Essential tool for determining enzyme specificity, active site mapping, and validating proteolytic activity in vitro.
• Cell Biology Studies: Applied in cell culture experiments to investigate the role of specific proteases in cellular signaling and disease models.

Basic Information

Product Name	Glycyl-Glycyl-Argininal
CAS No.	80434-79-3
Molecular Formula	C11H22N6O3
Molecular Weight	286.33 g/mol
Synonyms	Gly-Gly-Arg-H; GGR-H; H-Gly-Gly-Arg-H; Glycylglycyl-argininal; N2-(N-Glycylglycyl)-L-argininal; Trypsin Inhibitor Peptide Aldehyde; Boc-Gly-Gly-Arg-H (protected form); L-Argininal, N2-(N-glycylglycyl)-
EINECS	Contact for details

Quality Control

Our Glycyl-Glycyl-Argininal is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its sensitivity to oxidation and moisture. Allow the sealed container to reach room temperature before opening to minimize condensation and hydrolysis. For long-term stability, store desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details
Solubility	Soluble in DMSO, Methanol; Slightly soluble in Water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.