Description

4-Fluorobenzylphosphonic Acid is a high-purity organophosphorus compound featuring a fluorinated benzyl group, making it a versatile building block for advanced synthesis. Its unique structure is critical for introducing phosphonic acid functionality into target molecules, enabling the development of materials with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors seeking to create novel active ingredients or functional ligands.

Application

• Pharmaceutical Intermediate: Key synthon for the development of protease inhibitors, bone-targeting drugs (bisphosphonates), and other bioactive molecules.
• Agrochemical Synthesis: Building block for novel herbicides, plant growth regulators, and fungicides that utilize phosphonate chemistry.
• Ligand & Catalyst Preparation: Used to synthesize chelating ligands for metal catalysis, extraction, or sensor applications.
• Material Science: Precursor for surface modification agents, flame retardants, and corrosion inhibitors.
• Chemical Research: Valuable reagent in organic and medicinal chemistry for structure-activity relationship (SAR) studies.
• Coordination Chemistry: Serves as a linker or functional group in the construction of metal-organic frameworks (MOFs) and complexes.

Basic Information

Product Name	4-Fluorobenzylphosphonic Acid
CAS No.	80395-14-8
Molecular Formula	C7H8FO3P
Molecular Weight	190.11 g/mol
Synonyms	(4-Fluorophenyl)methylphosphonic Acid; p-Fluorobenzylphosphonic Acid; 4-Fluorobenzylphosphonate; [(4-Fluorophenyl)methyl]phosphonic Acid; Phosphonic acid, P-[(4-fluorophenyl)methyl]-; 80395-14-8; 4-Fluorobenzylphosphonic Acid Dihydrate (if applicable)
EINECS	Contact for details

Quality Control

Our 4-Fluorobenzylphosphonic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.