Description

Mast Cell Degranulating Peptide Hr-2 is a bioactive peptide known for its potent ability to induce the release of inflammatory mediators from mast cells. This compound is a critical research tool for studying allergic responses, immune system modulation, and inflammatory pathways. It is primarily utilized by researchers and developers in the fields of immunology, pharmacology, and drug discovery to investigate mast cell function and develop novel therapeutic agents.

Application

• Immunological Research: A key reagent for studying mast cell activation, degranulation mechanisms, and the release of histamine and other inflammatory mediators.
• Allergy and Inflammation Models: Used to establish in vitro and in vivo models for allergic reactions, asthma, and other inflammatory diseases.
• Drug Discovery & Screening: Employed in high-throughput screening assays to identify and evaluate potential anti-allergic or anti-inflammatory compounds that inhibit mast cell degranulation.
• Biochemical Studies: Facilitates research into signal transduction pathways and receptor interactions involved in immune cell response.
• Toxicology & Safety Pharmacology: Applied in studies assessing the potential of new chemical entities to cause pseudo-allergic reactions via mast cell activation.

Basic Information

Product Name	Mast Cell Degranulating Peptide Hr-2
CAS No.	80388-04-1
Molecular Formula	C95H147N31O26S
Molecular Weight	2195.5 g/mol
Synonyms	Mast Cell Degranulating Peptide; HR-2 Peptide; Peptide HR-2; MCD Peptide Hr-2; Hr-2; Mastoparan-like peptide HR-2; Wasp venom peptide HR-2; [Ile4, Leu5]-Mastoparan
EINECS	Contact for details

Quality Control

Our Mast Cell Degranulating Peptide Hr-2 is produced under stringent conditions to ensure the highest standards of purity and biological activity, suitable for sensitive research applications. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and MS for identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the peptide desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Biological Activity	Assessed by mast cell degranulation assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.