Description

Pyrido[2,3-D]Pyrimidine-6-Carboxylic Acid, 2-Amino-1,4-Dihydro-4-Oxo- (9Ci) is a high-purity heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its fused pyrido-pyrimidine core, which is a privileged scaffold in medicinal chemistry for designing bioactive molecules. This compound is essential for research and development laboratories in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel enzyme inhibitors and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of kinase inhibitors, anticancer agents, and other small-molecule therapeutics targeting the pyrido[2,3-d]pyrimidine pharmacophore.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and plant growth regulators with novel modes of action.
• Chemical Biology Probe Development: Serves as a core structure for creating fluorescent probes or activity-based protein profiling (ABPP) reagents to study biological pathways.
• Material Science Research: Potential monomer or precursor for constructing organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic semiconductors.
• Academic & Contract Research: Fundamental reagent for methodological development in organic chemistry and for exploring new synthetic routes to complex heterocycles.

Basic Information

Product Name	Pyrido[2,3-D]Pyrimidine-6-Carboxylic Acid, 2-Amino-1,4-Dihydro-4-Oxo- (9Ci)
CAS No.	80360-06-1
Molecular Formula	C8H6N4O3
Molecular Weight	206.16 g/mol
Synonyms	2-Amino-1,4-dihydro-4-oxopyrido[2,3-d]pyrimidine-6-carboxylic acid; 2-Amino-4-oxo-1,4-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid; 6-Carboxy-2-aminopyrido[2,3-d]pyrimidin-4(1H)-one; 2-Aminopyrido[2,3-d]pyrimidine-4(3H)-one-6-carboxylic acid; AOPC; Pyrido[2,3-d]pyrimidine-6-carboxylic acid, 2-amino-1,4-dihydro-4-oxo-; 80360-06-1
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with research-grade standards. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment and is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.