Description

4-Amidino-2-Benzoylphenyl 4-Guanidinobenzoate Dimethanesulfonate is a high-purity, non-peptidic small molecule compound designed for advanced research and development. This compound is valued for its potent and specific activity as a synthetic serine protease inhibitor, making it a critical tool in biochemical research and pharmaceutical development. It is primarily utilized by research institutions, pharmaceutical companies, and diagnostic manufacturers focused on developing novel therapeutic agents and diagnostic assays for conditions related to coagulation, fibrinolysis, and inflammation.

Application

• Biochemical Research: As a key reference standard and active inhibitor in enzymatic studies of serine proteases like thrombin, trypsin, and related enzymes.
• Pharmaceutical Development: Serves as a lead compound or intermediate in the R&D of novel anticoagulant and anti-inflammatory therapeutics.
• Diagnostic Reagent Formulation: Used in the manufacturing of in-vitro diagnostic (IVD) kits for clinical testing of blood coagulation pathways.
• Protease Inhibition Studies: Essential for investigating protease function and inhibition mechanisms in cellular and molecular biology.
• High-Throughput Screening (HTS): Employed as a control or reference compound in drug discovery screening assays.

Basic Information

Product Name	4-Amidino-2-Benzoylphenyl 4-Guanidinobenzoate Dimethanesulfonate
CAS No.	80251-34-9
Molecular Formula	C23H22N6O4 · 2CH4O3S
Molecular Weight	Contact for details
Synonyms	Benzamidine Mesylate Derivative; 4-Guanidinobenzoic Acid (4-Amidino-2-Benzoylphenyl) Ester Dimethanesulfonate; Thrombin Inhibitor (Non-peptidic); FOY-251; FOY 251; Ethyl p-(6-Guanidinohexanoyloxy)benzoate Methanesulfonate (related compound); Camostat impurity standard.
EINECS	Contact for details

Quality Control

Our 4-Amidino-2-Benzoylphenyl 4-Guanidinobenzoate Dimethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.