Description

H-Glu-His-Gly-Oh CAS NO 80251-23-6 is a synthetic tripeptide composed of the amino acids L-Glutamic acid, L-Histidine, and Glycine. This compound is of significant interest in biochemical research and pharmaceutical development due to its role as a peptide fragment and potential biological activity. It serves as a crucial building block and reference standard for researchers in life sciences. Key industries that utilize this peptide include pharmaceutical R&D, biotechnology, and academic research institutions focused on peptide chemistry and medicinal studies.

Application

• Pharmaceutical Research & Development: Used as a key intermediate or reference standard in the synthesis and study of novel therapeutic peptides and peptidomimetics.
• Biochemical Assay Development: Serves as a substrate, inhibitor, or control compound in enzymatic and receptor-binding assays to study biological pathways.
• Cosmetic & Dermatological Studies: Investigated for potential applications in skincare formulations due to the functional properties of its constituent amino acids.
• Academic Research: Employed in universities and research institutes for fundamental studies in peptide structure-activity relationships (SAR) and metabolism.
• Nutraceutical Exploration: Evaluated as a potential bioactive ingredient in specialized nutritional supplements targeting specific physiological functions.
• Diagnostic Reagent Component: May be used in the development of diagnostic kits and reagents that rely on specific peptide-antibody interactions.

Basic Information

Item	Detail
Product Name	H-Glu-His-Gly-Oh
CAS No.	80251-23-6
Molecular Formula	C13H20N6O6
Molecular Weight	356.34 g/mol
Synonyms	L-Glutamyl-L-histidylglycine; Glu-His-Gly; GHG; E-H-G; Glutamylhistidylglycine; H-Glu-His-Gly-OH; L-Glu-L-His-Gly; Tripeptide-1 (cosmetic ingredient name)
EINECS	Contact for details

Quality Control

Our H-Glu-His-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and chiral analysis to ensure the correct stereochemistry. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing the results against our stringent in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.