Description

8(p-Sulfophenyl)Theophylline is a specialized theophylline derivative characterized by a sulfophenyl substituent, which significantly alters its solubility and biological activity profile compared to the parent compound. This structural modification makes it a valuable intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel xanthine-based compounds, the study of adenosine receptor antagonism, and the development of analytical methods.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel xanthine derivatives with potential therapeutic applications.
• Biochemical Research: Used as a reference standard or tool compound in studies targeting adenosine receptors (A1, A2A, A2B, A3).
• Analytical Chemistry: Serves as a high-purity certified reference material (CRM) for method development and validation in HPLC, LC-MS, or NMR analysis.
• Life Science Research: Investigated for its role in modulating physiological processes such as bronchial relaxation, inflammation, and neural activity.
• Chemical Synthesis: Utilized in organic synthesis to introduce theophylline motifs into more complex molecular architectures.

Basic Information

Product Name	8(p-Sulfophenyl)Theophylline
CAS No.	80206-91-3
Molecular Formula	C13H12N4O4S
Molecular Weight	320.32 g/mol
Synonyms	8-(4-Sulfophenyl)theophylline; 1,3-Dimethyl-8-(4-sulfophenyl)-3,7-dihydro-1H-purine-2,6-dione; 8-(p-Sulfophenyl)theophylline; Theophylline-8-(4-sulfophenyl); 8-Sulfophenyltheophylline; 8-SPT; SP-Theophylline
EINECS	Contact for details

Quality Control

Our 8(p-Sulfophenyl)Theophylline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of related substances and residual solvents, to ensure it meets high-purity standards suitable for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.