Description

2-Methylphenyl-D-Alanine is a non-natural, chiral amino acid derivative featuring a D-configuration and a 2-methylphenyl (o-tolyl) side chain. This specific stereochemistry and aromatic substitution make it a valuable chiral building block and intermediate in advanced organic synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for applications requiring precise molecular architecture, such as in peptide-based drug discovery and the development of enzyme inhibitors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic peptides and peptidomimetics.
• Protease Inhibitor Synthesis: Used in constructing active components for inhibitors targeting specific enzymes.
• Chemical Biology Research: Serves as a building block for incorporating non-natural amino acids into peptides to study protein structure and function.
• Ligand Development: Employed in the synthesis of chiral ligands for asymmetric catalysis and metal complexation.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	2-Methylphenyl-D-Alanine
CAS No.	80126-54-1
Molecular Formula	C₁₀H₁₃NO₂
Molecular Weight	179.22 g/mol
Synonyms	D-2-Methylphenylalanine; (R)-2-Amino-3-(2-methylphenyl)propanoic acid; D-o-Methylphenylalanine; D-2-(2-Methylphenyl)alanine; D-α-Amino-o-toluic acid; H-D-2-MePhe-OH; (R)-2-Amino-3-o-tolylpropanoic acid
EINECS	Contact for details

Quality Control

Our 2-Methylphenyl-D-Alanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.