Description

Cyclo[L-Alanyl-L-Alanyl-(3R)-3-Hydroxyheptanoylglycyl-L-Valyl-D-Leucyl] is a complex cyclic hexapeptide of significant interest in advanced pharmaceutical research and development. This compound serves as a crucial building block or intermediate for the synthesis of novel therapeutic agents, particularly in the fields of oncology and immunology. It is primarily utilized by research institutions, biotechnology firms, and pharmaceutical companies engaged in peptide-based drug discovery and high-purity fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs) with targeted biological activity.
• Peptide-Based Drug Discovery: Serves as a core scaffold or a critical fragment for constructing novel peptide therapeutics in oncology and immunomodulation research.
• Biochemical Research: Used as a standard or reference compound in studies investigating protein-protein interactions, enzyme inhibition, and cell signaling pathways.
• High-Purity Fine Chemical Synthesis: Employed in multi-step organic synthesis for producing specialized, high-value compounds under cGMP or research-grade conditions.

Basic Information

Item	Details
Product Name	Cyclo[L-Alanyl-L-Alanyl-(3R)-3-Hydroxyheptanoylglycyl-L-Valyl-D-Leucyl]
CAS No.	80111-97-3
Molecular Formula	C30H51N7O8
Molecular Weight	637.77 g/mol
Synonyms	Cyclo(Ala-Ala-(3R)-3-Hydroxyheptanoyl-Gly-Val-D-Leu); Cyclic Hexapeptide 80111-97-3; [Cyclo(Ala2-β-OH-Hep-Gly-Val-D-Leu)]; FR901228 Analog; Depsipeptide Analog; FK228 Related Compound; Romidepsin Intermediate; L-Alanyl-L-Alanyl-(3R)-3-Hydroxyheptanoylglycyl-L-Valyl-D-Leucyl Cyclic Peptide
EINECS	Contact for details

Quality Control

Our Cyclo[L-Alanyl-L-Alanyl-(3R)-3-Hydroxyheptanoylglycyl-L-Valyl-D-Leucyl] is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.