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Cyclo[L-Alanyl-L-Alanyl-(3R)-3-Hydroxynonanoylglycyl-L-Valyl-D-Leucyl] CAS NO 80111-96-2


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CAS No.:80111-96-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Cyclo[L-Alanyl-L-Alanyl-(3R)-3-Hydroxynonanoylglycyl-L-Valyl-D-Leucyl] is a complex cyclic peptide compound of significant interest in advanced pharmaceutical research and development. Its unique structural features, including a hydroxynonanoyl side chain and a mix of L- and D-amino acids, make it a valuable scaffold for studying peptide conformation, stability, and biological activity. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutic agents, particularly in areas requiring sophisticated molecular templates. Its precise synthesis and high purity are critical for reliable experimental outcomes in drug discovery pipelines.

Application

  • Pharmaceutical Intermediate: Serves as a key building block or a structural motif in the synthesis of novel peptide-based drug candidates.
  • Biochemical Research: Used as a reference standard or a probe in studies investigating peptide-protein interactions, enzyme inhibition, and receptor binding.
  • Medicinal Chemistry: Acts as a core structure for structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties.
  • Antimicrobial Peptide Research: Investigated for its potential as a template in the development of new antimicrobial agents due to its cyclic and lipophilic characteristics.
  • Conformational Studies: Employed in spectroscopic studies (NMR, CD) to understand the relationship between cyclic peptide structure and biological function.

Basic Information

Item Details
Product Name Cyclo[L-Alanyl-L-Alanyl-(3R)-3-Hydroxynonanoylglycyl-L-Valyl-D-Leucyl]
CAS No. 80111-96-2
Molecular Formula C33H58N6O8
Molecular Weight 666.85 g/mol
Synonyms Cyclo(Ala-Ala-β-hydroxy-Gly-Val-D-Leu); Cyclic Hexapeptide 80111-96-2; L-Alanyl-L-alanyl-(3R)-3-hydroxynonanoylglycyl-L-valyl-D-leucyl cyclic peptide; [Cyclo(Ala2-β-OH-Non-Gly-Val-D-Leu)]; (3R)-3-Hydroxynonanoyl cyclic peptide; Cyclo[AA-(R)-3-HydroxyC9-Gly-V-DL]
EINECS Contact for details

Quality Control

Every batch of Cyclo[L-Alanyl-L-Alanyl-(3R)-3-Hydroxynonanoylglycyl-L-Valyl-D-Leucyl] is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC) Conforms to reference standard
Identification (MS) Conforms to structure
Purity (HPLC) ≥ 95.0%
Assay ≥ 97.0% (on anhydrous basis)
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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