Description

Acetyl-β-Endorphin (Human) is a synthetic, acetylated form of the endogenous neuropeptide β-endorphin. This modification enhances its stability and resistance to enzymatic degradation, making it a critical tool for advanced biochemical and pharmacological research. It is primarily utilized by research institutions and pharmaceutical developers investigating pain modulation, neuropsychiatric disorders, and the endogenous opioid system.

Application

• Neuroscience Research: Used as a reference standard and active agent in studies of opioid receptor binding, signal transduction, and neuropeptide function.
• Pain Mechanism Studies: Critical for in vitro and in vivo research exploring central and peripheral pain pathways and analgesic effects.
• Psychiatric Disorder Models: Applied in research on stress, addiction, depression, and other conditions linked to the endorphin system.
• Biochemical Assay Development: Serves as a high-purity calibrant and control in ELISA, RIA, and other immunoassay platforms.
• Drug Discovery & Development: Used in screening and characterizing novel analgesic or neuroprotective compounds targeting opioid receptors.
• Cell Signaling & Physiology: Employed to study the role of acetylated peptides in cellular communication and metabolic regulation.

Basic Information

Item	Detail
Product Name	Acetyl-β-Endorphin (Human)
CAS No.	80102-04-1
Molecular Formula	C164H251N39O48
Molecular Weight	3464.0 g/mol (approx.)
Synonyms	Acetyl-β-Endorphin; N-Acetyl-β-endorphin; Ac-β-EP; Acetylated β-Endorphin; N-Acetyl-β-endorphin (human); β-Lipotropin (61-91), N-acetyl-; H-Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH (N-acetyl); Opioid peptide
EINECS	Contact for details

Quality Control

Our Acetyl-β-Endorphin (Human) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, peptide content, and solvent residues is provided with every shipment to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere after opening and allow it to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by amino acid analysis)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Solubility	Soluble in water, acetic acid, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.