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Rat Gastrin C-Terminal Pentagastrin CAS NO 80063-35-0


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CAS No.:80063-35-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Rat Gastrin C-Terminal Pentagastrin CAS NO 80063-35-0 is a synthetic peptide fragment that mimics the biological activity of the C-terminal region of the gastrin hormone. This compound is a critical research tool for studying gastrointestinal physiology, hormone-receptor interactions, and gastric acid secretion mechanisms. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on metabolic and digestive system disorders.

Application

  • Pharmacological Research: Used as a standard agonist to stimulate gastrin/cholecystokinin-B (CCK-B) receptors in in vitro and in vivo studies.
  • Gastric Acid Secretion Studies: A key reagent for investigating the mechanisms and regulation of gastric acid production in animal models.
  • Diagnostic Agent Development: Serves as a reference compound in the development and validation of diagnostic assays for gastrin-related pathologies.
  • Drug Discovery & Screening: Employed in high-throughput screening (HTS) platforms to identify and evaluate novel antagonists or modulators of the gastrin receptor pathway.
  • Biochemical Standard: Acts as a quantitative standard in analytical techniques such as HPLC and mass spectrometry for peptide analysis.
  • Teaching & Academia: Used in university laboratories to demonstrate principles of endocrinology, peptide hormone action, and receptor signaling.

Basic Information

Product Name Rat Gastrin C-Terminal Pentagastrin
CAS No. 80063-35-0
Molecular Formula C37H49N7O9S
Molecular Weight 767.9 g/mol
Synonyms Pentagastrin; N-[(1,1-Dimethylethoxy)carbonyl]-β-alanyl-L-tryptophyl-L-methionyl-L-α-aspartyl-L-phenylalaninamide; Gastrin I (5-10) pentapeptide; AY-6608; Gastrin Pentapeptide; CCK-4 Analog; (tert-Butoxycarbonyl)-β-Ala-Trp-Met-Asp-Phe-NH2; BOC-β-Ala-Trp-Met-Asp-Phe-NH2
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Quality Control

Our Rat Gastrin C-Terminal Pentagastrin is manufactured under strict quality systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white powder
Identification (HPLC/MS) Conforms to reference standard
Purity (HPLC) ≥ 95.0%
Single Impurity (HPLC) ≤ 2.0%
Water Content (KF) ≤ 5.0%
Peptide Content (AAA) ≥ 80.0%
Solubility Soluble in water, DMSO, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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