Description

Suc-Gly-Pro-Amc CAS NO 80049-85-0 is a specialized fluorogenic peptide substrate designed for sensitive enzymatic assays. This compound is critical for researchers and quality control laboratories requiring precise measurement of protease activity, particularly dipeptidyl peptidase IV (DPP-IV). It is primarily utilized in the pharmaceutical, biotechnology, and diagnostic sectors for drug discovery, biochemical research, and enzyme characterization.

Application

• DPP-IV Enzyme Activity Assays: Primary substrate for the fluorometric or colorimetric detection and quantification of dipeptidyl peptidase IV activity in research and drug screening.
• Pharmaceutical Drug Discovery: Used in high-throughput screening (HTS) platforms to identify and characterize potential inhibitors for DPP-IV, a target for type 2 diabetes therapeutics.
• Biochemical Research: Essential tool for studying protease kinetics, enzyme specificity, and mechanism of action in academic and industrial laboratories.
• Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits and reagents for clinical research and biochemical analysis.
• Quality Control in Bioprocessing: Employed to monitor and validate the activity of enzyme preparations used in biomanufacturing processes.

Basic Information

Product Name	Suc-Gly-Pro-Amc
CAS No.	80049-85-0
Molecular Formula	C19H24N4O6
Molecular Weight	404.42 g/mol
Synonyms	Succinyl-Glycyl-Prolyl-7-Amino-4-methylcoumarin; Suc-Gly-Pro-AMC; Suc-Gly-Pro-7-amido-4-methylcoumarin; DPP-IV Substrate; DPP-IV Fluorogenic Substrate; Dipeptidyl Peptidase IV Substrate; H-Suc-Gly-Pro-AMC; N-Succinyl-Gly-Pro-AMC
EINECS	Contact for details

Quality Control

Our Suc-Gly-Pro-Amc is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive research applications. A detailed Certificate of Analysis (COA) with lot-specific data is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.