Description

5-[(3,4,5-Trimethoxyphenyl)Methyl]Pyrimidine-2,4-Diamine is a high-purity, specialized pyrimidine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacologically active intermediate and a versatile building block for the development of novel chemical entities. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating new therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential dihydrofolate reductase (DHFR) inhibitors and other targeted small molecule drugs.
• Research & Development: Used as a core scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Synthesis: Employed in the production of complex, high-value specialty chemicals for agrochemical and material science applications.
• Biochemical Research: Acts as a reference standard or a tool compound in biochemical assays and enzymatic studies.
• Academic Research: Utilized in university and institutional labs for exploring novel heterocyclic chemistry and reaction methodologies.

Basic Information

Product Name	5-[(3,4,5-Trimethoxyphenyl)Methyl]Pyrimidine-2,4-Diamine
CAS No.	8076-73-1
Molecular Formula	C14H18N4O3
Molecular Weight	290.32 g/mol
Synonyms	2,4-Diamino-5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine; 5-[(3,4,5-Trimethoxybenzyl)]-2,4-pyrimidinediamine; Trimethoprim Impurity; NSC 403169; 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine; Pyrimidine, 2,4-diamino-5-[(3,4,5-trimethoxyphenyl)methyl]-
EINECS	Contact for details

Quality Control

Our production of 5-[(3,4,5-Trimethoxyphenyl)Methyl]Pyrimidine-2,4-Diamine adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.