Description

Cascara CAS NO 8047-27-6 is a natural botanical extract derived from the dried bark of *Rhamnus purshiana*, commonly known as Cascara Sagrada. This product is valued for its standardized content of bioactive compounds, primarily anthraquinone glycosides, which are responsible for its key physiological effects. It is an essential ingredient for manufacturers in the pharmaceutical, nutraceutical, and herbal supplement industries seeking a reliable, high-quality botanical raw material for laxative and digestive health formulations.

Application

• Pharmaceutical Actives: Used as the active pharmaceutical ingredient (API) in over-the-counter (OTC) stimulant laxative preparations.
• Dietary Supplements & Nutraceuticals: Incorporated into capsules, tablets, and liquid extracts for natural digestive support and colon health formulas.
• Traditional Herbal Medicine (THM): Serves as a key component in herbal tinctures and teas formulated according to traditional pharmacopoeias.
• Veterinary Pharmaceuticals: Applied in veterinary medicine for digestive regulation in certain animal species.
• Clinical Research: Utilized as a standardized material in pharmacological and phytochemical research studies.

Basic Information

Product Name	Cascara
CAS No.	8047-27-6
Molecular Formula	Not Applicable (Complex Botanical Extract)
Molecular Weight	Not Applicable
Synonyms	Cascara Sagrada; Rhamnus purshiana bark extract; Sacred bark extract; Persian bark; Chittem bark; Bearberry; Purshiana bark; California buckthorn extract
EINECS	Contact for details

Quality Control

Our Cascara extract is produced and tested to meet stringent quality standards, including relevant monographs from the United States Pharmacopeia (USP), European Pharmacopoeia (Ph. Eur.), and other international compendia. Quality is assured through rigorous in-process controls and final batch testing for key markers such as total anthracene derivatives, moisture content, and microbial limits. A comprehensive Certificate of Analysis (COA) documenting purity, potency, and safety is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are sealed after each use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Description	Brown to dark brown powder or extract with characteristic odor
Identification (TLC/HPLC)	Complies with standard
Assay (Total Anthracene Derivatives)	≥ 8.0% (calculated as cascaroside A)
Loss on Drying	≤ 10.0%
Total Ash	≤ 6.0%
Microbial Limits	Meets Ph. Eur./USP requirements
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.