Description

Sodium Picosulfate is a high-purity pharmaceutical active ingredient, widely recognized for its potent stimulant laxative properties. Its primary value lies in its reliable and predictable action, making it a critical component in bowel preparation regimens prior to diagnostic procedures like colonoscopy. This compound is essential for manufacturers in the global pharmaceutical industry, particularly those producing prescription and over-the-counter laxative medications. Sodium Picosulfate CAS NO 10040-45-6 is supplied under stringent quality controls to meet the exacting standards of drug formulation.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the key component in prescription and OTC stimulant laxative medications.
• Bowel Preparation Solutions: Critical for formulating solutions used to cleanse the colon before surgical or diagnostic procedures such as colonoscopy.
• Pediatric and Geriatric Formulations: Used in specialized dosage forms designed for sensitive patient populations requiring predictable and gentle action.
• Veterinary Pharmaceuticals: Incorporated into animal health products for the treatment of constipation in various species.
• Clinical Research: Serves as a reference standard and raw material in pharmacological studies and new drug development.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of finished dosage forms.

Basic Information

Product Name	Sodium Picosulfate
CAS No.	10040-45-6
Molecular Formula	C18H13NNa2O8S2
Molecular Weight	481.41 g/mol
Synonyms	4,4'-(2-Pyridylmethylene)diphenol bis(hydrogen sulfate) sodium salt; Sodium Picosulphate; Picosulfate Sodium; Laxoberal; Laxoberon; Guttalax; Sodipic; Pico-Salax; Picolax
EINECS	233-125-1

Quality Control

Our Sodium Picosulfate is manufactured and tested to meet the highest pharmacopeial standards, including USP-NF and European Pharmacopoeia (Ph. Eur.) monographs. Every batch undergoes rigorous analytical testing for identity, potency, purity, and specified impurities to ensure it is suitable for use as a pharmaceutical active ingredient. A comprehensive Certificate of Analysis (COA) documenting all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in its original, sealed packaging until use to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Microbial Enumeration	Meets Ph. Eur. / USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.