Description

Docusate Calcium (500 Mg) is a high-purity pharmaceutical-grade calcium salt of docusate, a well-established anionic surfactant. This compound is valued for its exceptional efficacy as a stool softener and wetting agent, facilitating the mixing of aqueous and hydrophobic substances. It is a critical active pharmaceutical ingredient (API) for manufacturers in the pharmaceutical and nutraceutical industries, primarily used in the formulation of oral solid dosage forms such as tablets and capsules.

Application

• Pharmaceutical Formulations: Primary active ingredient in over-the-counter (OTC) and prescription stool softener tablets and capsules.
• Nutraceutical Supplements: Used in dietary supplement formulations aimed at promoting digestive regularity and comfort.
• Excipient Function: Acts as a surfactant and wetting agent in solid dosage forms to improve drug dissolution and bioavailability.
• Veterinary Medicine: Incorporated into animal health products for the management of constipation in various species.
• Clinical Use: Employed in hospital and clinical settings for patient populations requiring gentle laxative therapy.

Basic Information

Product Name	Docusate Calcium (500 Mg)
CAS No.	128-49-4
Molecular Formula	C40H74CaO4S2
Molecular Weight	883.3 g/mol
Synonyms	Calcium Dioctyl Sulfosuccinate; Dioctyl Calcium Sulfosuccinate; Docusate Calcium USP; Calcium Bis(2-ethylhexyl) Sulfosuccinate; Surfak; Colace Calcium; 1,4-Bis(2-ethylhexyl) Sulfobutanedioic Acid Calcium Salt
EINECS	204-900-5

Quality Control

Our Docusate Calcium is manufactured and tested to meet or exceed current United States Pharmacopeia (USP) monograph standards, ensuring it is suitable for pharmaceutical applications. Each batch undergoes rigorous analytical testing, including assay, identification, and impurity profiling. A comprehensive Certificate of Analysis (COA) documenting purity, physical characteristics, and compliance is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a low-humidity environment to prevent degradation and caking.

Specification

Item	Specification
Appearance	White or off-white, waxy solid
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF Titration)	NMT 2.0%
Heavy Metals	NMT 20 ppm
Residual Solvents	Complies with USP/ICH guidelines
Microbial Enumeration	Complies with USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.