Description

Sennoside E CAS NO 11137-63-6 is a high-purity, naturally derived anthraquinone glycoside, recognized for its potent biological activity. This compound is a critical standard and active ingredient, valued for its consistent quality and reliable performance in demanding applications. It is primarily sought by manufacturers and research institutions in the pharmaceutical, nutraceutical, and analytical chemistry sectors for product development and quality control.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and impurity profiling of senna-based laxative formulations in compliance with pharmacopoeial monographs (e.g., USP, EP, JP).
• Active Pharmaceutical Ingredient (API): Serves as a key bioactive component in the formulation of standardized herbal medicinal products and over-the-counter (OTC) laxatives.
• Nutraceutical and Dietary Supplement Manufacturing: Incorporated into natural health products aimed at supporting digestive health, requiring precise standardization for efficacy and safety.
• Biochemical and Pharmacological Research: Employed in in-vitro and in-vivo studies to investigate mechanisms of action, metabolic pathways, and potential new therapeutic applications.
• Quality Control & Analytical Testing: Essential for the development and validation of analytical methods such as HPLC and LC-MS for the quantification of sennosides in raw materials and finished products.

Basic Information

Product Name	Sennoside E
CAS No.	11137-63-6
Molecular Formula	C42H38O20
Molecular Weight	862.75 g/mol
Synonyms	Sennoside E; (R)-Sennoside E; Sennoside E (from Cassia angustifolia); Cassioside; 5,5'-Bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo[9,9'-bianthracene]-2,2'-dicarboxylic acid dimethyl ester
EINECS	Contact for details

Quality Control

Every batch of Sennoside E is produced and tested under a strict quality management system. We provide material that meets high-purity standards suitable for pharmaceutical and research applications. Comprehensive testing includes identification, assay, and related substance analysis via validated HPLC methods. A detailed Certificate of Analysis (COA) is supplied with each shipment, ensuring full traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.