Description

Casanthranol is a purified, standardized anthranol glycoside complex derived from cascara sagrada, primarily valued for its consistent and predictable biological activity. This botanical extract is a key active ingredient in the formulation of stimulant laxatives, providing a reliable therapeutic effect. It is essential for manufacturers in the pharmaceutical and nutraceutical industries seeking high-quality, standardized botanical actives for digestive health products.

Application

• Pharmaceutical Active Ingredient: Primary use as the active component in stimulant laxative formulations for the treatment of occasional constipation.
• Over-the-Counter (OTC) Drug Manufacturing: Used in the production of tablets, capsules, and liquid preparations for digestive health.
• Nutraceutical and Dietary Supplements: Incorporated into herbal supplement blends aimed at supporting bowel regularity and colon health.
• Veterinary Pharmaceuticals: Applied in veterinary medicine for digestive aid formulations for companion animals and livestock.
• Standardized Botanical Extracts: Serves as a reference standard or a key ingredient in standardized cascara sagrada extracts.

Basic Information

Product Name	Casanthranol
CAS No.	8024-48-4
Molecular Formula	Complex mixture of anthranol glycosides (primarily cascarosides)
Molecular Weight	N/A (Natural product mixture)
Synonyms	Cascara Sagrada Extract (Standardized); Peristaltine; Casanthrol; Rhamnus Purshiana Extract (Standardized); Cascarosides; 10-Hydroxyanthracene Glycosides; Botanical Laxative Principle
EINECS	Contact for details

Quality Control

Our Casanthranol is produced and tested to meet stringent pharmaceutical-grade standards. Quality is assured through comprehensive analytical testing, including HPLC for active constituent profiling and quantification. We provide full traceability and support compliance with relevant pharmacopoeial monographs (e.g., USP-NF). Certificates of Analysis (COA) detailing purity, identity, and strength are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Fine, yellowish-brown to brown powder
Identification (HPLC/IR)	Complies
Assay (Total Anthranols)	Contact for details
Loss on Drying	≤ 5.0%
Ash	≤ 5.0%
Heavy Metals	≤ 20 ppm
Microbiological Limits	Complies with Ph. Eur./USP

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.