Description

Acid Citrate-Dextrose is a sterile, anticoagulant solution formulated from citric acid, sodium citrate, and dextrose. This compound is critically important as a preservative and stabilizer for blood and blood-derived products, ensuring their viability and safety during storage and transport. It is an essential material for manufacturers in the pharmaceutical, biotechnological, and clinical diagnostics industries, particularly those involved in blood banking, vaccine production, and cell culture media preparation.

Application

• Blood Collection and Preservation: Primary anticoagulant solution used in blood collection bags (e.g., ACD-A, ACD-B formulations) to prevent coagulation and maintain red blood cell integrity.
• Apheresis Procedures: Used as an anticoagulant during platelet and plasma apheresis to ensure product quality and donor safety.
• Cell Culture and Microbiology: Serves as a buffering agent and nutrient source in specialized cell culture media and microbial growth formulations.
• Molecular Biology: Used as a component in buffers for nucleic acid extraction and stabilization, helping to chelate metal ions and inhibit nucleases.
• Pharmaceutical Manufacturing: Acts as a stabilizer and excipient in certain injectable drug formulations and biological products.
• In-Vitro Diagnostics (IVD): A key reagent in diagnostic kits and systems for hematological testing and blood typing.

Basic Information

Product Name	Acid Citrate-Dextrose
CAS No.	8013-89-6
Molecular Formula	Mixture of C6H8O7, C6H5Na3O7, C6H12O6
Molecular Weight	N/A (Sterile Solution)
Synonyms	ACD Solution; Anticoagulant Citrate Dextrose Solution; Acid-Citrate-Dextrose; Citrate Dextrose Solution; ACD-A; ACD-B; Anticoagulant Solution A; USP Anticoagulant Citrate Dextrose Solution
EINECS	Contact for details

Quality Control

Our Acid Citrate-Dextrose solution is manufactured under strict quality systems. It is tested to meet stringent specifications for sterility, apyrogenicity, pH, and component concentration, aligning with relevant pharmacopeial standards (e.g., USP, EP). A comprehensive Certificate of Analysis (COA), detailing all test results, is provided with each batch to ensure traceability and compliance for our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the primary container label. Do not freeze. The product is light-sensitive and should be stored in its original packaging until use.

Specification

Item	Specification
Description	Clear, colorless to slightly yellow sterile solution
Identification (IR)	Conforms to standard
pH	4.5 - 5.5
Assay (Citric Acid)	98.0 - 102.0 % of label claim
Assay (Sodium Citrate)	98.0 - 102.0 % of label claim
Assay (Dextrose)	98.0 - 102.0 % of label claim
Sterility Test	Sterile
Bacterial Endotoxins	< 0.5 EU/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.