Description

3-(Trifluoromethoxy)Phenol is a high-purity fluorinated phenolic compound, serving as a critical building block in advanced chemical synthesis. Its unique trifluoromethoxy substituent imparts enhanced lipophilicity and metabolic stability, making it a valuable intermediate for creating high-performance materials and active ingredients. This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with improved properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in areas requiring fluorinated motifs for bioactivity and patent life extension.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances efficacy and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structure in the synthesis of fluorinated components for electronic display and lighting technologies.
• Polymer & Resin Modifier: Incorporated to impart specific properties like chemical resistance, thermal stability, or altered surface energy in high-performance polymers.
• Organic Synthesis Building Block: A versatile reagent for introducing the -OCF3 functional group into more complex molecular architectures via coupling or substitution reactions.

Basic Information

Product Name	3-(Trifluoromethoxy)Phenol
CAS No.	827-99-6
Molecular Formula	C7H5F3O2
Molecular Weight	178.11 g/mol
Synonyms	3-Hydroxybenzotrifluoride ether; m-(Trifluoromethoxy)phenol; 3-Trifluoromethoxyphenol; 1-Hydroxy-3-(trifluoromethoxy)benzene; Phenol, 3-(trifluoromethoxy)-; α,α,α-Trifluoro-m-cresol methyl ether
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethoxy)Phenol is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider using an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.