Description

5-Fluoro-2-(Trifluoromethyl)Aniline is a high-value fluorinated aromatic amine building block, essential for introducing both fluorine and aniline functionalities into complex molecular architectures. Its unique trifluoromethyl and fluoro substituents make it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) with enhanced properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel compounds with improved metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to increased biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to enhance chemical resistance, thermal stability, and surface properties.
• Dye & Pigment Intermediate: Utilized in the synthesis of specialized fluorinated dyes and pigments for high-performance applications.
• Research & Development: A valuable reagent in medicinal chemistry and material science R&D for structure-activity relationship (SAR) studies and novel compound libraries.

Basic Information

Product Name	5-Fluoro-2-(Trifluoromethyl)Aniline
CAS No.	827-20-3
Molecular Formula	C7H5F4N
Molecular Weight	179.12 g/mol
Synonyms	2-Amino-4-fluorobenzotrifluoride; 4-Fluoro-2-(trifluoromethyl)aniline; 2-(Trifluoromethyl)-4-fluoroaniline; 5-Fluoro-α,α,α-trifluoro-o-toluidine; 5-Fluoro-2-trifluoromethylphenylamine; 827-20-3; Benzenamine, 5-fluoro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials such as strong oxidizing agents and acids. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.