Description

5-Aminosalicylic Acid (CAS NO 89-57-6) is a key pharmaceutical intermediate and active pharmaceutical ingredient (API) with significant therapeutic and industrial importance. Its primary value lies in its anti-inflammatory properties, making it a cornerstone in the treatment of inflammatory bowel diseases. This high-purity compound is essential for manufacturers in the pharmaceutical, research, and fine chemical synthesis sectors seeking reliable, high-quality raw materials for their critical processes.

Application

• Pharmaceutical API: Primary active ingredient in medications for ulcerative colitis and Crohn's disease (e.g., mesalamine formulations).
• Chemical Synthesis Intermediate: Crucial building block for synthesizing more complex azo dyes, pharmaceutical derivatives, and other salicylate-based compounds.
• Research & Development: Used in biochemical and pharmacological research to study anti-inflammatory pathways and develop new therapeutic agents.
• Analytical Reference Standard: Serves as a high-purity standard in HPLC, LC-MS, and other analytical methods for quality control and regulatory testing.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals where a high-purity amino-substituted salicylic acid is required.

Basic Information

Product Name	5-Aminosalicylic Acid
CAS No.	89-57-6
Molecular Formula	C7H7NO3
Molecular Weight	153.14 g/mol
Synonyms	Mesalamine; Mesalazine; 5-ASA; 5-Amino-2-hydroxybenzoic Acid; Fisalamine; Asacol; Rowasa; Pentasa; USP Mesalamine; 2-Hydroxy-5-aminobenzoic Acid; 5-Aminosalicylate
EINECS	201-919-1

Quality Control

Our 5-Aminosalicylic Acid is manufactured under strict quality management systems. It undergoes rigorous analytical testing to ensure it meets or exceeds relevant pharmacopeial standards, including USP and EP monographs where applicable. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.